Product information CaReS

CaReS^® is an innovative technology for the treatment of joint lesions. The patented 3D cell-collagen type I matrix provides a high cell activity and functionality and an almost natural production of cartilage-specific collagen type II.

The collagen type I matrix was developed in collaboration with the Fraunhofer Institute for Interfacial Engineering and Biotechnology (IGB, Institut für Grenzflächen- und Bioverfahrenstechnik) in Stuttgart, Germany. Unlike the carrier media in the collagen foam or resorbable fleece the chondrocytes can be clearly defined and controlled in the collagen. Moreover, only a small quantity of chondrocytes is needed for a gel matrix based cell transplantation. During surgery, height and shape of the CaReS^® implant can be adapted to the defect.

Properties:

• Clearly defined cell matrix constructs
• Due to 0-passages production times are reduced considerably
• Chondrocytes in the CaReS^® matrix have a high cell vitality
• CaReS^® grafts provide an excellent bonding to the surrounding cartilage.
• Mini-arthrotomy makes surgery simple and fast
• The surrounding structures are not damaged by sutures or pins.
• The osmotic properties of CaReS^® ensure optimal nourishment of the chondrocytes.
• CaReS^® is manufactured in accordance with the principles of Good Manufacturing Practice (GMP).